Peptide Database

Peptide NameSLAY-screened peptide P5102

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC107H180N24O30

DescriptionStandard

        ITTQLILTFELNIVTIIIHS
    

Molecular Weight2282.72 Da

Isoelectric Point (pI)5.24

Net Charge (pH 7.0)-1.15

Net Charge (pH 7.4) -1.40

Charge Density (pH 7.0) -0.0575

GRAVY Index1.41

Hydrophobic Moment 0.27

Boman Index0.53

Instability Index41.18

Aliphatic Index 190.00

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 869.53

LogP -4.59

H-bond Donors 30.0

H-bond Acceptors 30.0

Rotatable Bonds 75.0

Heavy Atoms 161.0

Ring Count 2.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0299235 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/