Peptide Database

Peptide NameSomapacitan

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length191 amino acids

Chemical FormulaC987H1526N262O300S8

DescriptionStandard

        FPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSCVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF
    

Molecular Weight22118.77 Da

Isoelectric Point (pI)5.27

Net Charge (pH 7.0)-4.99

Net Charge (pH 7.4) -5.48

Charge Density (pH 7.0) -0.0261

GRAVY Index-0.42

Hydrophobic Moment 0.68

Boman Index-0.05

Instability Index42.08

Aliphatic Index 81.68

Aromaticity 0.1152

Extinction Coeff. Reduced 17420.00

Extinction Coeff. Oxidized 17670.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 9147.67

LogP -109.77

H-bond Donors 318.0

H-bond Acceptors 306.0

Rotatable Bonds 704.0

Heavy Atoms 1557.0

Ring Count 34.0

Amide Bonds 212.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0211766 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyInsulin

Tax ID9606

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsLipidation

Bio-Activity Profile

Function

Hormone replacement

TargetCHO

Half-LifeThe elimination half life of somapacitan is 2-3 days.[L15661]

RECORD: Rec_0223843 VERIFIED: NO