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MYP_099748
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Basic Information
Spinulosain-A1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
28 amino acids
C125H215N37O38S4
Standard
Sequence
GFLNTAMNTVTNLAGTLMDKAKCKIRGC
Physicochemical Analysis
2972.53 Da
9.39
2.74
2.50
0.0978
0.10
0.49
0.05
-16.95
76.79
0.0357
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1236.47
-14.83
45.0
45.0
102.0
204.0
1.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0056280 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Spinulosain
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
23-28
Bio-Activity Profile
-
PaperH. Wang et al. / Peptides 30 (2009) 273-282. The novel antimicrobial peptides from skin of Chinese broad-folded frog, Hylarana latouchii (Anura:Ranidae) Evidence URLhttps://www.uniprot.org/uniprotkb/E7EKI9/entry
RECORD: Rec_0127382 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0163987 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic
Human erythrocytes
200 μM
MIC
RECORD: Rec_0242470 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Psychrobacter faecalis X29
400 μM
MIC
PMID24055160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24055160/
RECORD: Rec_0344920 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Ranatuerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
200 μM
Hemolysis
PMID24055160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24055160/