Peptide Database

Peptide NameToxin C13S1C1

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC289H487N83O80S8

DescriptionStandard

        RICYSHKLLQAKTTKTCEENSCYKRSLPKIPLIIIGRGCGCPLTLPFLRIKCCTSDKCN
    

Molecular Weight6660.99 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)7.77

Net Charge (pH 7.4) 7.38

Charge Density (pH 7.0) 0.1316

GRAVY Index-0.14

Hydrophobic Moment 0.53

Boman Index-0.08

Instability Index57.56

Aliphatic Index 87.63

Aromaticity 0.0508

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2638.08

LogP -26.35

H-bond Donors 101.0

H-bond Acceptors 97.0

Rotatable Bonds 223.0

Heavy Atoms 460.0

Ring Count 8.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0086211 VERIFIED: YES

Provenance & Taxonomy

Organismvenom of the Eastern green mamba,Dendroaspis angusticeps [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

TargetHUVEC

Activity57±3 μg/mL

MethodLC50

RECORD: Rec_0167535 VERIFIED: YES

Provenance & Taxonomy

Organismvenom of the Eastern green mamba,Dendroaspis angusticeps [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

TargetHuman erythrocytes

Activity600 μg/mL

MethodLC50

RECORD: Rec_0169597 VERIFIED: YES

Provenance & Taxonomy

Organismvenom of the Eastern green mamba,Dendroaspis angusticeps [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetMDA-MB-231

Activity62±2 μg/mL

MethodLC50

RECORD: Rec_0250222 VERIFIED: YES

Provenance & Taxonomy

Organismvenom of the Eastern green mamba,Dendroaspis angusticeps [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetA549

Activity56±4 μg/mL

MethodLC50

RECORD: Rec_0286070 VERIFIED: YES

Provenance & Taxonomy

Organismvenom of the Eastern green mamba,Dendroaspis angusticeps [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetHT-29

Activity110±4 μg/mL

MethodLC50