Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC481H774N126O128S7

DescriptionStandard

        MKLFLVLIILLFEVPTDGARLKKCFNNITGYCRKKCKVGEIYEIGCLSGRLCCVNYEENKKHVPVKKPHTHSGEKPTIHQDYAILPTVTIFTV
    

Molecular Weight10594.51 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)5.79

Net Charge (pH 7.4) 5.25

Charge Density (pH 7.0) 0.0623

GRAVY Index-0.01

Hydrophobic Moment 0.60

Boman Index0.06

Instability Index31.15

Aliphatic Index 98.39

Aromaticity 0.0860

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4060.05

LogP -29.89

H-bond Donors 145.0

H-bond Acceptors 145.0

Rotatable Bonds 353.0

Heavy Atoms 742.0

Ring Count 17.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124208 VERIFIED: NO

Provenance & Taxonomy

OrganismCebus imitator [Animal]

FamilyDefensin

Tax ID9516

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence