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MYP_099687
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Basic Information
Vaby D
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
30 amino acids
C127H194N36O42S6
Standard
Sequence
GLPVCGETCFGGTCNTPGCTCDPWPVCTRN
Physicochemical Analysis
3089.51 Da
4.37
-1.30
-1.59
-0.0432
-0.04
0.32
0.13
56.17
32.33
0.0667
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1211.68
-17.20
46.0
47.0
87.0
211.0
7.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0280406 VERIFIED: YES
Provenance & Taxonomy
Viola abyssinica [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Cytotoxic Anti-Gram-negative
Salmonella enterica serovar Typhimurium
90 μM
MIC
PMID21434649;20558471 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21434649/
RECORD: Rec_0387253 VERIFIED: YES
Provenance & Taxonomy
Ethiopian highlands [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperCyclotides from an extreme habitat: characterization of cyclic peptides from Viola abyssinica of the Ethiopian highlands
RECORD: Rec_0390512 VERIFIED: YES
Provenance & Taxonomy
Viola abyssinica [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Cytotoxic Anti-Gram-positive
Staphylococcus aureus
90 μM
MIC
PMID21434649;20558471 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21434649/
RECORD: Rec_0398248 VERIFIED: YES
Provenance & Taxonomy
Viola abyssinica [Plant]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral
PaperPubMed PMID: 21434649 PMID21434649 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21434649/
RECORD: Rec_0422223 VERIFIED: YES
Provenance & Taxonomy
Viola abyssinica [Plant]
Cyclotide
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Cytotoxic Anti-Gram-negative
Escherichia coli
50 μM
MIC
PMID21434649;20558471 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21434649/
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