Peptide Database

Peptide NameLeptin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC705H1182N206O216S4

DescriptionStandard

        VPIRKVQDDTKTLIKTIVARINDISHTQSVSSKQRVAGLDFIPGLQPVLSLSRMDQTLAIYQQILNSLHSRNVVQISNDLENLRDLLHLLASSKSCPLPRARGLETFESLGGVLEASLYSTEVVALNRLQAALQDMLRRLDLSPGC
    

Molecular Weight16128.44 Da

Isoelectric Point (pI)8.73

Net Charge (pH 7.0)1.99

Net Charge (pH 7.4) 1.58

Charge Density (pH 7.0) 0.0136

GRAVY Index-0.02

Hydrophobic Moment 0.65

Boman Index0.00

Instability Index49.77

Aliphatic Index 118.84

Aromaticity 0.0274

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6844.51

LogP -73.29

H-bond Donors 239.0

H-bond Acceptors 225.0

Rotatable Bonds 548.0

Heavy Atoms 1131.0

Ring Count 13.0

Amide Bonds 161.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0367551 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

FamilyLeptin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic