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MYP_099577
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Standard
14 amino acids
C74H116N20O21
Standard
Sequence
RLPSEFDLSAFLRA
Physicochemical Analysis
1621.83 Da
6.07
-0.24
-0.44
-0.0169
0.10
0.31
-0.01
73.13
97.86
0.1429
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
671.69
-5.28
24.0
21.0
51.0
115.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0044777 VERIFIED: YES
Provenance & Taxonomy
Pleurotus cornucopiae [Fungus]; Agaricus bisporus [Fungus]
ACE-inhibitory peptide
5341
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
460 μg/mL
IC50
PaperCharacterization of an antihypertensive angiotensin I-converting enzyme inhibitory peptide from the edible mushroom Hypsizygus marmoreus. PMID24380081 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24380081/
RECORD: Rec_0089756 VERIFIED: NO
Provenance & Taxonomy
Pleurotus cornucopiae [Fungus]; Agaricus bisporus [Fungus]
ACE-inhibitory peptide
5341
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory Antioxidant
ACE
52 μM
IC50
PaperVegetable foods: A cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities. PMID23598136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598136/
RECORD: Rec_0100080 VERIFIED: NO
Provenance & Taxonomy
Pleurotus cornucopiae [Fungus]; Fungi [Fungus]
4751; 4751
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperVegetable foods: a cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities PMID23598136 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598136/
RECORD: Rec_0178774 VERIFIED: NO
Provenance & Taxonomy
Pleurotus cornucopiae [Fungus]; Agaricus bisporus [Fungus]
ACE-inhibitory peptide
5341
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
50 mmHg
SBP decrease
PaperAntihypertensive peptides from food proteins: a review. PMID22249830 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22249830/
RECORD: Rec_0374038 VERIFIED: YES
Provenance & Taxonomy
Pleurotus cornucopiae [Fungus]
Angiotensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
460 μg/mL
IC50
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