Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length352 amino acids

Chemical FormulaC1779H2830N522O526S

DescriptionStandard

        LAKPTDKPNVFTASIASDIPDVKIGFDSRPPVEVTRNFFKKETINHLTPVKGLSKISPAKAVGFWGGARSRDAIVSFPKESGREPIYVSVIPVSTPNDIKSRQDDIDRQKLLWDAFHPVEVAERELVLAQKELDHADNDVKAKRSTLARLEPELAEAKWNAENVIRGWGGWQDYHKKQVNAYKSKQAEYSAANAALNNALERRKEKEKKVKEAKDKFDKENKRNKPGVATGKGKPVGNKWLDNADKESGAPIPDRIADKLRGKEFKNFDDFRKKFWEEVSKDPELSKQFKNQNKTNIQKGKAPFAKKKDQVGGRERFELHHDKPISQDGGVYDMDNLRITTPKRHIDIHRGK
    

Molecular Weight39978.75 Da

Isoelectric Point (pI)9.65

Net Charge (pH 7.0)18.51

Net Charge (pH 7.4) 17.75

Charge Density (pH 7.0) 0.0526

GRAVY Index-1.01

Hydrophobic Moment 0.65

Boman Index-0.24

Instability Index34.92

Aliphatic Index 66.53

Aromaticity 0.0767

Extinction Coeff. Reduced 45950.00

Extinction Coeff. Oxidized 45950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0347766 VERIFIED: YES

Provenance & Taxonomy

OrganismEdwardsiella tarda [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)