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MYP_099519
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Basic Information
NZ16K18R
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
40 amino acids
C191H290N56O54S6
Standard
Sequence
GFGCNGPWNEDDLRCKNRCKSIKGYKGGYCAKGGFVCKCY
Physicochemical Analysis
4427.08 Da
9.04
4.70
4.39
0.1174
-0.72
0.34
-0.13
11.42
29.25
0.1500
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1807.23
-20.00
69.0
65.0
147.0
307.0
8.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0286942 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S. pneumoniae CVCC2350
0.454 μM
MIC
PMID28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28229435/
RECORD: Rec_0323469 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus ATCC 6538
0.114 μM
MIC
PMID28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28229435/
RECORD: Rec_0333369 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
S. pneumoniae CVCC1.8722
0.454 μM
MIC
PMID28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28229435/
RECORD: Rec_0334952 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus ATCC 43300
0.114 μM
MIC
PMID28229435 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28229435/
RECORD: Rec_0337440 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Plectasin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S-pullorum CVCC1789
>7.273 μM
MIC
PaperDesign and pharmacodynamics of recombinant NZ2114 histidine mutants with improved activity against methicillin-resistant Staphylococcus aureus.
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