Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length92 amino acids

Chemical FormulaC477H775N123O128S7

DescriptionStandard

        MKLFLVLIILLFEVLTDGARLKKCFNNVTGYCRKKCKVGEIHEIGCLSGKLCCVNDEENKKHVPFKKPHQQPVELSVQQDYVILPTITIFTV
    

Molecular Weight10505.46 Da

Isoelectric Point (pI)8.79

Net Charge (pH 7.0)3.71

Net Charge (pH 7.4) 3.22

Charge Density (pH 7.0) 0.0403

GRAVY Index0.12

Hydrophobic Moment 0.62

Boman Index0.08

Instability Index31.24

Aliphatic Index 108.91

Aromaticity 0.0761

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4034.81

LogP -28.54

H-bond Donors 141.0

H-bond Acceptors 142.0

Rotatable Bonds 357.0

Heavy Atoms 735.0

Ring Count 14.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0383911 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic