Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length141 amino acids

Chemical FormulaC721H1129N195O214S9

DescriptionStandard

        MNLLLLTFIICGLLTQATKASFGPQKCWKNNVGYCRRRCLDTERYIRLCRNKLSCCISIIWSYEHLRRPEPPMIHIDDITFDYTDWETFTGTSITRFPDAITFEDHTFRGNTITKATASETSTEKIPESKPPPSQISLVDS
    

Molecular Weight16241.44 Da

Isoelectric Point (pI)7.57

Net Charge (pH 7.0)0.71

Net Charge (pH 7.4) 0.21

Charge Density (pH 7.0) 0.0051

GRAVY Index-0.34

Hydrophobic Moment 0.63

Boman Index-0.03

Instability Index50.96

Aliphatic Index 76.81

Aromaticity 0.0993

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6581.64

LogP -65.06

H-bond Donors 239.0

H-bond Acceptors 227.0

Rotatable Bonds 526.0

Heavy Atoms 1139.0

Ring Count 29.0

Amide Bonds 148.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0297326 VERIFIED: NO

Provenance & Taxonomy

OrganismCarlito syrichta [Animal]

FamilyBeta-defensin; Defensin

Tax ID1868482

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic