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MYP_099478
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Basic Information
UL131 90-106
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Standard
17 amino acids
C81H140N36O27
Standard
Sequence
SDFRRQNRRGGTNKRTT
Physicochemical Analysis
2050.20 Da
12.00
4.46
4.25
0.2624
-2.43
0.64
-0.92
105.23
0.00
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1111.93
-18.27
42.0
32.0
72.0
144.0
1.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0289945 VERIFIED: YES
Provenance & Taxonomy
Human betaherpesvirus 5 [Virus]
Virus-derived peptide
10359;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor Immunomodulatory
Human cytomegalovirus (Immunostimulaton); MCR-5
GFP assay
PaperPeptides from cytomegalovirus UL130 and UL131 proteins induce high titer antibodies that block viral entry into mucosal epithelial cells. | Saccoccio FM, Sauer AL, Cui X, Armstrong AE, Habib el-SE, Johnson DC, Ryckman BJ, Klingelhutz AJ, Adler SP, McVoy MA. | Vaccine. 2011 | PMID:21310190 PMID21310190 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21310190/
RECORD: Rec_0392962 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 64.7%, C 35.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/