Peptide Database

Peptide NameLEAP-2

Function Ontology

—

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC179H299N59O51S6

DescriptionStandard

        MTPFWRGVSLRPIGASCRDNSECITMLCRRNRCLLSAA
    

Molecular Weight4286.04 Da

Isoelectric Point (pI)9.47

Net Charge (pH 7.0)3.46

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0912

GRAVY Index-0.00

Hydrophobic Moment 0.54

Boman Index-0.10

Instability Index68.32

Aliphatic Index 77.11

Aromaticity 0.0526

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1791.79

LogP -20.80

H-bond Donors 70.0

H-bond Acceptors 61.0

Rotatable Bonds 139.0

Heavy Atoms 295.0

Ring Count 5.0

Amide Bonds 39.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0249215 VERIFIED: YES

Provenance & Taxonomy

OrganismAcanthisitta chloris [Animal]

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)