Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC166H268N50O56S2

DescriptionStandard

        KCNTATCATQRLTNFLVHSSNNLGPVLSPTNVGSNTY
    

Molecular Weight3924.34 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)1.83

Net Charge (pH 7.4) 1.54

Charge Density (pH 7.0) 0.0493

GRAVY Index-0.26

Hydrophobic Moment 0.46

Boman Index0.03

Instability Index10.91

Aliphatic Index 71.08

Aromaticity 0.0541

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1734.10

LogP -26.50

H-bond Donors 61.0

H-bond Acceptors 61.0

Rotatable Bonds 123.0

Heavy Atoms 274.0

Ring Count 5.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0018986 VERIFIED: YES

Provenance & Taxonomy

OrganismCricetulus barabensis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)