Peptide Database

Peptide NameLantibiotic mutacin-2 (Lantibiotic mutacin H-29B) (Mutacin II)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length53 amino acids

Chemical FormulaC260H399N73O82S5

DescriptionStandard

        MNKLNSNAVVSLNEVSDSELDTILGGNRWWQGVVPTVSYECRMNSWQHVFTCC
    

Molecular Weight6019.71 Da

Isoelectric Point (pI)4.90

Net Charge (pH 7.0)-2.43

Net Charge (pH 7.4) -2.75

Charge Density (pH 7.0) -0.0459

GRAVY Index-0.19

Hydrophobic Moment 0.55

Boman Index0.05

Instability Index42.78

Aliphatic Index 76.98

Aromaticity 0.0943

Extinction Coeff. Reduced 17990.00

Extinction Coeff. Oxidized 18115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2527.12

LogP -28.45

H-bond Donors 90.0

H-bond Acceptors 86.0

Rotatable Bonds 194.0

Heavy Atoms 420.0

Ring Count 10.0

Amide Bonds 60.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0043021 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus mutans [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetMicrococcus luteus (Gram-negative)

RECORD: Rec_0045578 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus mutans [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetA. viscosus (Gram-positive)

RECORD: Rec_0047254 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus mutans [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0102023 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus mutans [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetP. acnes

RECORD: Rec_0106355 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus mutans [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStreptococcus (Gram-positive)

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