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MYP_099345
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Basic Information
Human RK-31
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
31 amino acids
C169H292N54O45
Standard
Sequence
RKSKEKIGKEFKRIVQRIKDFLRNLVPRTES
Physicochemical Analysis
3800.46 Da
11.04
6.76
6.55
0.2182
-1.16
0.97
-0.50
28.36
81.61
0.0645
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1689.22
-15.23
61.0
52.0
139.0
268.0
3.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0078497 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20070037744A1/en PatentUS 2007/0037744 A1
RECORD: Rec_0130548 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Group A Staphylococcus aureus (GAS)
8 μM
MIC
PMID14978112 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14978112/
RECORD: Rec_0159165 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus mprF
8 μM
MIC
PMID14978112 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14978112/
RECORD: Rec_0177125 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Cathelicidin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
16 μM
MIC
PMID14978112 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14978112/
RECORD: Rec_0189178 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Natural peptide
10090
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium smegmatis mc2 155
PMID21790937 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21790937/
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