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MYP_099304
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Basic Information
IN(1-10)
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition
Standard
10 amino acids
C53H83N17O14S
Standard
Sequence
WQCLTLTHRG
Physicochemical Analysis
1214.40 Da
8.26
0.84
0.57
0.0837
-0.38
0.36
-0.02
12.23
78.00
0.1000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
515.14
-4.60
20.0
17.0
37.0
85.0
3.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0239088 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Anti-HIV-1 Integrase inhibitor Replication inhibition
HIV-1; TZM-bl cells
68 %
virus replication inhibition at 62.5 μM
PaperPubMed PMID: 19850483 PMID19850483 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19850483/
RECORD: Rec_0314860 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Anti-HIV-1 Integrase inhibitor Replication inhibition
HIV-1 integrase
70-80 %
integrase inhibition at 78 μM
PMID19850483 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19850483/
RECORD: Rec_0319976 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Anti-HIV-1 Integrase inhibitor Replication inhibition
HIV-1 integrase
64 %
integration inhibition at 62.5 μM
PaperPubMed PMID: 19850483 PMID19850483 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19850483/
RECORD: Rec_0368671 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Anti-HIV-1 Integrase inhibitor Replication inhibition
HIV-1 integrase; HIV-1
integrase and virus-replication inhibition assays
PaperPubMed PMID: 19850483 PMID19850483 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19850483/
RECORD: Rec_0374684 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Integrase inhibition Anti-HIV-1 Integrase inhibitor Replication inhibition
HIV-1; TZM-bl cells
68 %
virus replication inhibition at 62.5 μM
PaperPeptide inhibitors of HIV-1 integrase: from mechanistic studies to improved lead compounds. PMID19850483 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19850483/
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