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MYP_099281
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Basic Information
Neutrophil cationic peptide 2 precursor
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiviral
Standard
31 amino acids
C164H262N54O41S6
Standard
Sequence
RRCICTTRTCRFPYRRLGTCLFQNRVYTFCC
Physicochemical Analysis
3838.56 Da
9.80
6.70
6.41
0.2161
-0.22
0.67
-0.28
60.19
47.10
0.1613
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1588.62
-17.03
67.0
54.0
121.0
265.0
6.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006017 VERIFIED: YES
Provenance & Taxonomy
Cavia porcellus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID8173076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8173076/
RECORD: Rec_0043992 VERIFIED: YES
Provenance & Taxonomy
Cavia porcellus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Three Disulfide bridges. Seq differs from GNCP-1 only at position 21 (L here and I for GNCP-1)
Bio-Activity Profile
Antimicrobial Antifungal Antiviral
PaperPurification, primary structure, and biological activity of guinea pig neutrophil cationic peptides.
RECORD: Rec_0048535 VERIFIED: YES
Provenance & Taxonomy
Cavia porcellus [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PMID8173076 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8173076/
RECORD: Rec_0180998 VERIFIED: YES
Provenance & Taxonomy
Cavia porcellus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiviral
Staphylococcus aureus
PaperPubMed PMID: 8173076 | PubMed PMID: 10738945 PMID8173076;10738945 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8173076/
RECORD: Rec_0183870 VERIFIED: NO
Provenance & Taxonomy
Cavia porcellus [Animal]
10141
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
3-31; 5-20; 10-30
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Antiviral
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