Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC327H543N91O86S9

DescriptionStandard

        MKAFLLTLAALVLLSQVTSGSAEKCWNLRGSCREKCIRNEKLYIFCMSGKLCCLKPKFQPNMLQR
    

Molecular Weight7413.95 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)7.44

Net Charge (pH 7.4) 7.12

Charge Density (pH 7.0) 0.1145

GRAVY Index0.10

Hydrophobic Moment 0.42

Boman Index0.00

Instability Index40.79

Aliphatic Index 93.08

Aromaticity 0.0769

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2885.95

LogP -24.74

H-bond Donors 107.0

H-bond Acceptors 103.0

Rotatable Bonds 255.0

Heavy Atoms 513.0

Ring Count 8.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0281587 VERIFIED: NO

Provenance & Taxonomy

OrganismVulpes lagopus [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence