Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length125 amino acids

Chemical FormulaC546H899N157O169S3

DescriptionStandard

        MVAAASAILFSPAAGGGSDRVPGRDLNAMFALNAQLLAGPDVKIEPGATSVNLPERGHLVNSNGQMALQLLKTGDTLPAAVPVLNAVRDAATGLDRITVPAVAGAPERTILVNPAPPPAAPSDTA
    

Molecular Weight12463.12 Da

Isoelectric Point (pI)5.11

Net Charge (pH 7.0)-2.40

Net Charge (pH 7.4) -2.68

Charge Density (pH 7.0) -0.0192

GRAVY Index0.22

Hydrophobic Moment 0.77

Boman Index0.17

Instability Index45.48

Aliphatic Index 100.88

Aromaticity 0.0160

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5067.67

LogP -58.92

H-bond Donors 166.0

H-bond Acceptors 171.0

Rotatable Bonds 388.0

Heavy Atoms 875.0

Ring Count 17.0

Amide Bonds 134.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0222842 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyPyocin/Colicin

Tax ID28901

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli