Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length229 amino acids

Chemical FormulaC1148H1775N269O347S11

DescriptionStandard

        QIDDLAEVDYSLSSLPAVFRPFIDLDLKGVVFPAGKFTDSPCMAASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFNINTEIFGSIIPEVAKYSVTPNPVMLKLMATEIPTIRLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNIAANTSISLNIFDQKLMGSLCLNRLRFSLAHSNVGSFEVLLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight25249.68 Da

Isoelectric Point (pI)4.28

Net Charge (pH 7.0)-13.15

Net Charge (pH 7.4) -13.50

Charge Density (pH 7.0) -0.0574

GRAVY Index0.31

Hydrophobic Moment 0.60

Boman Index0.22

Instability Index47.52

Aliphatic Index 97.55

Aromaticity 0.1135

Extinction Coeff. Reduced 11920.00

Extinction Coeff. Oxidized 12045.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240832 VERIFIED: NO

Provenance & Taxonomy

OrganismGymnorhina tibicen (Australian magpie) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria