Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length502 amino acids

Chemical FormulaC2553H3931N633O725S20

DescriptionStandard

        MHTKAVQLLWGCFFLWNLYISSAQTVYPGIKARVTQQALDYGVLAGMEMIEQMVKEKKIPDLEGSESLEFLKVDYVNYNFSNIKIHAFSFPNTSLAFVPGVGIKALTNHGTANISTDWEVKSPLFQDTGGADLFLSGVFFTGIIVLARNNFGHPIMKLQDCYAQVSHAHVSFSGDLSVLYNSFAEPMEKPILKNLNEMLCPMIMSEVGALNANLSMLEVLTKIDNYTLLDYSLISSPEITENYMELNLKGVFYPLDNLSDPPFSPVPFALPEHHDSMLYIGISEFFFKSASFAYFTAGAFNVTLSMKEVRRVHGWDSQLQHFVLLKIAEIYLLSQPFMVQVMATEPPAISLQPGNFTLDIPASIVLLAQTENSTAEAIVSMDFVASTSVGLVILGQRLVCSLSLNRFRLSLPESNRSNIEVLRFENILSSILHFGILPLANGTLQSHAHPGVTLSSFLPPFQGFLLISTDLKYETSLKQQPSFHGWEGLNLISGQWRGKPAA
    

Molecular Weight55732.63 Da

Isoelectric Point (pI)5.44

Net Charge (pH 7.0)-13.26

Net Charge (pH 7.4) -14.35

Charge Density (pH 7.0) -0.0264

GRAVY Index0.19

Hydrophobic Moment 0.63

Boman Index0.20

Instability Index39.03

Aliphatic Index 100.22

Aromaticity 0.1096

Extinction Coeff. Reduced 55350.00

Extinction Coeff. Oxidized 55600.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0386773 VERIFIED: NO

Provenance & Taxonomy

OrganismNeovison vison [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence