‹ ›
MYP_099126
← PREVIOUS NEXT → BACK
Basic Information
Alloferon-1 [H1K]
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
13 amino acids
C52H81N21O16
Standard
Sequence
KGVSGHGQHGVHG
Physicochemical Analysis
1256.33 Da
8.77
1.02
0.66
0.0785
-0.88
0.33
0.06
-21.23
44.62
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
587.90
-9.03
20.0
20.0
41.0
89.0
3.0
13.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0290607 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alloferon
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0326295 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alloferon
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Non-cytotoxic
Vero cells; LLC-MK2 cells; HEp-2 cells
no cytotoxicity
cytotoxicity assay up to 218.75 μg/mL
PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0329252 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alloferon
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Human herpesvirus 1 strain McIntyre; HEp-2 cells
241.9 μg/mL
IC50 (antiviral cytopathic-effect assay)
PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0368883 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alloferon
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Coxsackievirus B2 strain 971 PT; LLC-MK2 cells
157.73 μg/mL
IC50 (antiviral cytopathic-effect assay)
PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0373106 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 15.4%, T 46.2%, C 38.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
FIRST PREV 1 2 3 4 5 NEXT LAST
Showing 5 records · Page 4 of 5