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MYP_099126
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Basic Information
Alloferon-1 [H1K]
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C52H81N21O16
Standard
Sequence
KGVSGHGQHGVHG
Physicochemical Analysis
1256.33 Da
8.77
1.02
0.66
0.0785
-0.88
0.33
0.06
-21.23
44.62
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
587.90
-9.03
20.0
20.0
41.0
89.0
3.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0290607 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alloferon
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral Cytotoxic
PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0326295 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alloferon
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Vero cells,LLC-MK2 cells and Hep-2 cells up to 218
PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0329252 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alloferon
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
inhibition of virus replication in Hep-2 cells
241.9 μg/mL
IC50
PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0368883 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alloferon
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Coxsackie virus 971 PT(971 PT CVB2):inhibition of virus replication in LLC-MK2 cells
157.73 μg/mL
IC50
PMID21766388 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21766388/
RECORD: Rec_0373106 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 15.4%, T 46.2%, C 38.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
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