Peptide Database

Peptide NameV13SL (V681 peptide derivative)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length26 amino acids

Chemical FormulaC136H223N35O35

DescriptionStandard

        KWKSFLKTFKSASKTVLHTALKAISS
    

Molecular Weight2908.44 Da

Isoelectric Point (pI)10.70

Net Charge (pH 7.0)5.84

Net Charge (pH 7.4) 5.58

Charge Density (pH 7.0) 0.2247

GRAVY Index-0.10

Hydrophobic Moment 0.65

Boman Index0.01

Instability Index6.56

Aliphatic Index 82.69

Aromaticity 0.1154

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1153.25

LogP -10.53

H-bond Donors 43.0

H-bond Acceptors 42.0

Rotatable Bonds 100.0

Heavy Atoms 206.0

Ring Count 5.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0424296 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermAcetylation

Other ModsD-Ser at 13

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetPseudomonas aeruginosa H187

Activity18.3 μg/mL

MethodMIC

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