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MYP_099015
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Basic Information
THP-3
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
25 amino acids
C106H175N37O31S4
Standard
Sequence
LSCKRGTCHFGRCPSHLIKGSCSGG
Physicochemical Analysis
2592.01 Da
9.31
3.89
3.53
0.1557
-0.23
0.67
-0.05
64.37
46.80
0.0400
0.00
250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1087.28
-16.14
44.0
41.0
85.0
178.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0272353 VERIFIED: YES
Provenance & Taxonomy
Meleagris gallopavo [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
S. enteriditis
8 μg/mL
MIC
PaperIsolation of antimicrobial peptides from avian heterophils.
RECORD: Rec_0285059 VERIFIED: YES
Provenance & Taxonomy
Meleagris gallopavo [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
16 μg/mL
MIC
PaperIsolation of antimicrobial peptides from avian heterophils.
RECORD: Rec_0316629 VERIFIED: NO
Provenance & Taxonomy
Meleagris gallopavo [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Anti-Gram-positive Non-hemolytic Non-ribosomal
Staphylococcus
Qualitative functional evidence
PMID7964174 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7964174/; https://www.uniprot.org/uniprotkb/P80393/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0330855 VERIFIED: YES
Provenance & Taxonomy
Meleagris gallopavo [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
S-typhimurium
>16 μg/mL
MIC
PaperIsolation of antimicrobial peptides from avian heterophils.
RECORD: Rec_0346401 VERIFIED: YES
Provenance & Taxonomy
Meleagris gallopavo [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
B-avium
>16 μg/mL
MIC
PaperIsolation of antimicrobial peptides from avian heterophils.
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