Peptide Database

Peptide NameAll-D-Magainin-2

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium

Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition

Antimicrobial ▸ Antifungal

Antiparasitic ▸ Antimalarial

Antiparasitic ▸ Antiprotozoal

Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium

Antiparasitic ▸ Antiprotozoal ▸ Anti-Trypanosoma

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Antiviral

Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Antiviral ▸ Virucidal activity

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Insecticidal/Pest control ▸ Insecticidal activity

Reproductive biology ▸ Contraceptive activity ▸ Spermicidal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Wound healing/Regeneration ▸ Wound healing

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC114H180N30O29S

DescriptionStandard

        GIGKFLHSAKKFGKAFVGEIMNS
    

Molecular Weight2466.90 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.59

Charge Density (pH 7.0) 0.1237

GRAVY Index0.08

Hydrophobic Moment 0.69

Boman Index0.17

Instability Index-0.10

Aliphatic Index 72.17

Aromaticity 0.1304

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 957.13

LogP -7.89

H-bond Donors 33.0

H-bond Acceptors 34.0

Rotatable Bonds 86.0

Heavy Atoms 174.0

Ring Count 4.0

Amide Bonds 23.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0425832 VERIFIED: YES

Provenance & Taxonomy

OrganismXenopus laevis [Animal]

FamilyMagainin

Tax ID8355

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial

Target647V(G2)

Activity54.1 μM

MethodIC50

FIRST PREV 1 ... 62 63 64

Showing 1 records on this page Ã‚Â· Page 64 of 64