Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length101 amino acids

Chemical FormulaC506H809N137O152S10

DescriptionStandard

        MSVMKPYLMTISILLILVPKTPGDLFRSYYGNSREPWIPCQLYHGMCRNTCRNNEIQYLTCPSDQKCCLKLSVKVARSNNVKDYDSDSNLSVTNISSYSKI
    

Molecular Weight11564.31 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)4.53

Net Charge (pH 7.4) 4.14

Charge Density (pH 7.0) 0.0448

GRAVY Index-0.29

Hydrophobic Moment 0.63

Boman Index-0.03

Instability Index43.77

Aliphatic Index 83.86

Aromaticity 0.0891

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16305.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4697.53

LogP -49.36

H-bond Donors 169.0

H-bond Acceptors 168.0

Rotatable Bonds 380.0

Heavy Atoms 805.0

Ring Count 17.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0271681 VERIFIED: NO

Provenance & Taxonomy

OrganismPanthera leo [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence