Peptide Database

Peptide NameLantibiotic lichenicidin VK21 A2 (LchA2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC311H512N90O107S7

DescriptionStandard

        MKTMKNSAAREAFKGANHPAGMVSEEELKALVGGNDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC
    

Molecular Weight7448.39 Da

Isoelectric Point (pI)7.67

Net Charge (pH 7.0)0.56

Net Charge (pH 7.4) 0.22

Charge Density (pH 7.0) 0.0078

GRAVY Index-0.25

Hydrophobic Moment 0.62

Boman Index0.01

Instability Index31.57

Aliphatic Index 54.31

Aromaticity 0.0278

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3152.93

LogP -44.84

H-bond Donors 114.0

H-bond Acceptors 116.0

Rotatable Bonds 242.0

Heavy Atoms 515.0

Ring Count 8.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0100195 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus licheniformis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetBacillus subtilis (Gram-positive)

RECORD: Rec_0101066 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus licheniformis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetB. amyloliquefaciens (Gram-positive)

RECORD: Rec_0130713 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus licheniformis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetPseudomonas aeruginosa (Gram-negative)

RECORD: Rec_0180365 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus licheniformis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetMicrococcus luteus (Gram-negative)

RECORD: Rec_0227575 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus licheniformis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetRhodococcus sp. (Gram-positive)

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