Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length65 amino acids

Chemical FormulaC326H541N91O87S8

DescriptionStandard

        MKAFLLTLAALVLLSQVTSGSAEKCWNLRGSCREKCIRNEKLYIFCTSGKLCCLKPKFQPNMLQR
    

Molecular Weight7383.86 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)7.44

Net Charge (pH 7.4) 7.12

Charge Density (pH 7.0) 0.1145

GRAVY Index0.06

Hydrophobic Moment 0.42

Boman Index-0.01

Instability Index34.03

Aliphatic Index 93.08

Aromaticity 0.0769

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2906.18

LogP -26.11

H-bond Donors 108.0

H-bond Acceptors 103.0

Rotatable Bonds 253.0

Heavy Atoms 512.0

Ring Count 8.0

Amide Bonds 70.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0195060 VERIFIED: NO

Provenance & Taxonomy

OrganismVulpes vulpes [Bacterium]

FamilyDefensin

Tax ID9627

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence