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MYP_098901
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Basic Information
Magainin-2 [I2L][K11R][I20A]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
23 amino acids
C111H174N32O29S
Standard
Sequence
GLGKFLHSAKRFGKAFVGEAMNS
Physicochemical Analysis
2452.83 Da
10.29
2.85
2.59
0.1238
-0.09
0.77
0.08
9.39
59.57
0.1304
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
993.01
-9.78
35.0
34.0
84.0
173.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0168232 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
1000 μM
Hemolysis
PMID9042968;9166783 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9042968/
RECORD: Rec_0185278 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
75 μM
MIC
PMID9042968;9166783 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9042968/
RECORD: Rec_0226819 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
150 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/9166783/ PMID9166783 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9166783/
RECORD: Rec_0298538 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli
75 μM
MIC
PMID9042968;9166783 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9042968/
RECORD: Rec_0308945 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 60.9%, C 39.1% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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