Peptide Database

Peptide NameCholecystokinin-12

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC72H103N17O20S

DescriptionStandard

        IKDRDYLGWMDF
    

Molecular Weight1558.75 Da

Isoelectric Point (pI)4.43

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.45

Charge Density (pH 7.0) -0.1032

GRAVY Index-0.71

Hydrophobic Moment 0.16

Boman Index-0.08

Instability Index19.54

Aliphatic Index 65.00

Aromaticity 0.2500

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 619.26

LogP -2.06

H-bond Donors 22.0

H-bond Acceptors 20.0

Rotatable Bonds 50.0

Heavy Atoms 110.0

Ring Count 4.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0067311 VERIFIED: YES

Provenance & Taxonomy

OrganismCarassius auratus [Animal]

FamilyCholecystokinin

Tax ID7957

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

C-TermAmidation

Other Mods6:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Reproductive regulator Myotropic Feeding regulator

Half-LifeMammalian: 20 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0347024 VERIFIED: NO