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MYP_098887
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Basic Information
CXCL6
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
77 amino acids
C369H630N104O104S4
Standard
Sequence
GPVSAVLTELRCTCLRVTLRVNPKTIGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDSGNKKN
Physicochemical Analysis
8315.84 Da
9.75
7.72
7.44
0.1003
-0.04
0.74
-0.01
45.47
103.64
0.0260
0.00
250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3361.14
-33.49
116.0
116.0
282.0
581.0
8.0
84.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0015060 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative
Streptococcus dysgalactiae subsp. equisimilis
PMID18443119;23533582 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18443119/
RECORD: Rec_0084293 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic
S. pyogenes, S. dysgalactiae subsp. equisimilis, Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa
0.06-0.37 μM
MBC
PaperThe human CXC chemokine granulocyte chemotactic protein 2 (GCP-2)/CXCL6 possesses membrane-disrupting properties and is antibacterial
RECORD: Rec_0176929 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PMID18443119;23533582 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18443119/
RECORD: Rec_0224628 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic
PaperPubMed PMID: 18443119 PMID18443119 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18443119/
RECORD: Rec_0245018 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID18443119;23533582 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18443119/
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