Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC552H880N144O169S3

DescriptionStandard

        PDLSGYEKYGLGNVKYNISKIHVTAVEFPSASISLIPGTGIKLVIGNASLTIDMNWNIRTWMFKDTGRSTVYISKVFVTAIFSTSLDNTGHTSISLASCRTTSGDIEIKLNGKS
    

Molecular Weight12333.95 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)3.12

Net Charge (pH 7.4) 2.93

Charge Density (pH 7.0) 0.0274

GRAVY Index0.04

Hydrophobic Moment 0.49

Boman Index0.13

Instability Index14.02

Aliphatic Index 94.04

Aromaticity 0.0877

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 16960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5030.01

LogP -55.46

H-bond Donors 181.0

H-bond Acceptors 177.0

Rotatable Bonds 409.0

Heavy Atoms 868.0

Ring Count 17.0

Amide Bonds 120.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0125401 VERIFIED: NO

Provenance & Taxonomy

OrganismThinocorus orbignyianus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria