Peptide Database

Peptide NameSubstance P

Function Ontology

Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Tachykinin peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC61H98N18O13S

DescriptionStandard

        KPRPHQFIGLM
    

Molecular Weight1323.61 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)1.85

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.1678

GRAVY Index-0.52

Hydrophobic Moment 0.18

Boman Index-0.03

Instability Index6.04

Aliphatic Index 70.91

Aromaticity 0.0909

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 496.43

LogP -2.40

H-bond Donors 16.0

H-bond Acceptors 17.0

Rotatable Bonds 41.0

Heavy Atoms 93.0

Ring Count 4.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0184911 VERIFIED: YES

Provenance & Taxonomy

OrganismOryzias latipes [Animal]

FamilySubstance P

Tax ID8090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor modulation

Half-LifeMammalian: 1.3 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0223928 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

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