Peptide Database

Peptide NameProlactin release-inhibiting factor 1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Reproductive neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length56 amino acids

Chemical FormulaC285H449N83O91S4

DescriptionStandard

        NTEHLVESFQEMGKEVDQMAEPQHFECTVHWPRSPLRDLRGALESLIEEEARQKKM
    

Molecular Weight6622.38 Da

Isoelectric Point (pI)5.03

Net Charge (pH 7.0)-4.96

Net Charge (pH 7.4) -5.35

Charge Density (pH 7.0) -0.0886

GRAVY Index-0.96

Hydrophobic Moment 0.73

Boman Index-0.20

Instability Index83.84

Aliphatic Index 62.68

Aromaticity 0.0536

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2829.14

LogP -26.84

H-bond Donors 96.0

H-bond Acceptors 93.0

Rotatable Bonds 226.0

Heavy Atoms 463.0

Ring Count 10.0

Amide Bonds 60.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0324669 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyProlactin release-inhibiting factor

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Growth regulation Development regulation Receptor modulation

Half-LifeMammalian: 1.4 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0373615 VERIFIED: NO