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MYP_098719
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Basic Information
Brevinin-1RL1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
24 amino acids
C130H206N32O27S2
Standard
Sequence
FFPLIAGLAARFLPKIFCSITKRC
Physicochemical Analysis
2713.35 Da
10.11
3.74
3.50
0.1558
1.02
0.71
0.29
35.68
110.00
0.1667
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
931.34
-3.48
35.0
33.0
85.0
191.0
6.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0308673 VERIFIED: YES
Provenance & Taxonomy
Frog Skin Secretion [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
B16-F10
6.65±0.33 μM
IC50
PaperPubMed PMID: 33916789 PMID33916789 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33916789/
RECORD: Rec_0311713 VERIFIED: YES
Provenance & Taxonomy
Frog Skin Secretion [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes: Moderate Hemolysis
PaperPubMed PMID: 33916789 PMID33916789 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33916789/
RECORD: Rec_0313515 VERIFIED: YES
Provenance & Taxonomy
Frog Skin Secretion [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
HCT 116
5.87±0.15 μM
IC50
PaperPubMed PMID: 33916789 PMID33916789 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33916789/
RECORD: Rec_0327507 VERIFIED: YES
Provenance & Taxonomy
Rana limnocharis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae ATCC 700603
2.5 μg/mL
MIC
PMID26452973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26452973/
RECORD: Rec_0338001 VERIFIED: YES
Provenance & Taxonomy
Frog Skin Secretion [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
SW480
10.37±0.40 μM
IC50
PaperPubMed PMID: 33916789 PMID33916789 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33916789/
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