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MYP_098719
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Basic Information
Brevinin-1RL1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
24 amino acids
C130H206N32O27S2
Standard
Sequence
FFPLIAGLAARFLPKIFCSITKRC
Physicochemical Analysis
2713.35 Da
10.11
3.74
3.50
0.1558
1.02
0.71
0.29
35.68
110.00
0.1667
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
931.34
-3.48
35.0
33.0
85.0
191.0
6.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0202364 VERIFIED: YES
Provenance & Taxonomy
Rana limnocharis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli IS218#
PMID26452973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26452973/
RECORD: Rec_0222589 VERIFIED: YES
Provenance & Taxonomy
Rana limnocharis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida parapsilosis ATCC 22019
20 μg/mL
MIC
PMID26452973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26452973/
RECORD: Rec_0228924 VERIFIED: YES
Provenance & Taxonomy
Frog Skin Secretion [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-231
5.44±0.33 μM
IC50
PaperPubMed PMID: 33916789 PMID33916789 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33916789/
RECORD: Rec_0232994 VERIFIED: YES
Provenance & Taxonomy
Rana limnocharis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
5 μg/mL
MIC
RECORD: Rec_0263465 VERIFIED: YES
Provenance & Taxonomy
Rana limnocharis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 90028
10 μg/mL
MIC
PMID26452973 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26452973/
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