Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC484H776N122O129S7

DescriptionStandard

        MKLFLVLIILLFEVPTDGARLKKCFNNITGYCRKKCKVGEIYEIGCLSGKLCCVNYEENKKHVPVKKPHTHSGEKPTIYQDYAILPTVTIFTV
    

Molecular Weight10592.53 Da

Isoelectric Point (pI)9.07

Net Charge (pH 7.0)5.70

Net Charge (pH 7.4) 5.21

Charge Density (pH 7.0) 0.0613

GRAVY Index0.01

Hydrophobic Moment 0.60

Boman Index0.08

Instability Index28.00

Aliphatic Index 98.39

Aromaticity 0.0968

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4015.72

LogP -28.04

H-bond Donors 143.0

H-bond Acceptors 145.0

Rotatable Bonds 353.0

Heavy Atoms 742.0

Ring Count 17.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0348402 VERIFIED: NO

Provenance & Taxonomy

OrganismSaimiri boliviensis boliviensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence