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MYP_098663
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Antitumor
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C104H200N26O19
Standard
Sequence
GIIKKIIKKIIKKIIKKI
Physicochemical Analysis
2118.86 Da
10.85
7.75
7.54
0.4307
0.49
0.87
0.05
-33.01
195.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
766.18
0.72
27.0
27.0
85.0
149.0
0.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0143781 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Alpha-helical proteins
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Cytotoxic
HL-60
5 μM
Cytotoxicity assay
PMID24246647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24246647/
RECORD: Rec_0206338 VERIFIED: YES
Provenance & Taxonomy
Alpha-helical proteins [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HL-60 Approx
70 %
Cytotoxicity
PaperPubMed PMID: 24246647 PMID24246647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24246647/
RECORD: Rec_0210778 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Toxic Hemolytic Antitumor
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0213342 VERIFIED: YES
Provenance & Taxonomy
Alpha-helical proteins [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
HeLa Approx
80 %
Cytotoxicity
PaperPubMed PMID: 24246647 PMID24246647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24246647/
RECORD: Rec_0257511 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Bacillus subtilis ATCC 23857
2 μM
MIC
PaperHigh Therapeutic Index alpha-Helical AMPs and Their Therapeutic Potential on Bacterial Lung and Skin Wound Infections
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