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MYP_098655
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Basic Information
ToAP3
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C81H138N18O19S
Standard
Sequence
FIGMIPGLIGGLISAIK
Physicochemical Analysis
1700.14 Da
8.75
0.76
0.55
0.0447
1.69
0.38
0.70
9.98
166.47
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
566.38
-1.35
19.0
21.0
56.0
119.0
2.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002262 VERIFIED: YES
Provenance & Taxonomy
Tityus obscurus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Bacillus subtilis
2.5-5 μM
MIC
PaperActivity of Scorpion Venom-Derived Antifungal Peptides against Planktonic Cells of Candida spp. and Cryptococcus neoformans and Candida albicans Biofilms
RECORD: Rec_0026971 VERIFIED: YES
Provenance & Taxonomy
Tityus obscurus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
inactive: Escherichia coli
>200 μM
MIC
PaperActivity of Scorpion Venom-Derived Antifungal Peptides against Planktonic Cells of Candida spp. and Cryptococcus neoformans and Candida albicans Biofilms
RECORD: Rec_0053622 VERIFIED: YES
Provenance & Taxonomy
Tityus obscurus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antibiofilm Antifungal
C. glabrata ATCC 90030
400 μM
MIC
PMID27917162 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27917162/
RECORD: Rec_0099391 VERIFIED: NO
Provenance & Taxonomy
Tityus obscurus [Animal]
Non-disulfide-bridged peptide (NDBP) superfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Antifungal Fungicide Anti-Candida Anti-Gram-positive Anti-inflammatory Cytotoxic Hemolytic Non-ribosomal
Candida spp., Cryptococcus neoformans, Mycobacterium abscessus
Qualitative functional evidence
PMID27917162 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27917162/; https://www.uniprot.org/uniprotkb/P0DQT2/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0101311 VERIFIED: YES
Provenance & Taxonomy
Isometrus maculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
2.5-5 μM
MIC
PMID28941793 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28941793/
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