Peptide Database

Peptide NameV8E22I33C45-40kDa PEG

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC185H277N45O59S

DescriptionStandard

        HVEGTFTSDVSSYLEEQAAKEFIAWLIKGGPSSGAPPPC
    

Molecular Weight4107.51 Da

Isoelectric Point (pI)4.57

Net Charge (pH 7.0)-3.15

Net Charge (pH 7.4) -3.43

Charge Density (pH 7.0) -0.0809

GRAVY Index-0.19

Hydrophobic Moment 0.48

Boman Index0.17

Instability Index51.52

Aliphatic Index 65.13

Aromaticity 0.1026

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1621.90

LogP -16.82

H-bond Donors 55.0

H-bond Acceptors 58.0

Rotatable Bonds 126.0

Heavy Atoms 290.0

Ring Count 10.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0151052 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGlucagon

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermPEGylation

Bio-Activity Profile

Function

Insulinotropic

MethodEC50

Half-LifeMonkey plasma (Subcutaneous), in vivo; 221760 s