Peptide Database

Peptide NameLeptin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC713H1181N197O222S3

DescriptionStandard

        VPIHKVQDDTKTLIKTIVTRINDISHTQSVSARQRVTGLDFIPGLHPILSLSKMDQTLAVYQQILTSLPSQNVLQIAHDLENLRDLLHLLAFSKSCSLPQTRGLQKPESLDGVLEASLYSTEVVALSRLQGSLQDILQQLDLSPEC
    

Molecular Weight16161.39 Da

Isoelectric Point (pI)5.90

Net Charge (pH 7.0)-2.83

Net Charge (pH 7.4) -3.35

Charge Density (pH 7.0) -0.0194

GRAVY Index-0.03

Hydrophobic Moment 0.66

Boman Index0.05

Instability Index54.53

Aliphatic Index 120.14

Aromaticity 0.0274

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6750.68

LogP -69.99

H-bond Donors 231.0

H-bond Acceptors 227.0

Rotatable Bonds 546.0

Heavy Atoms 1135.0

Ring Count 16.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346638 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyLeptin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic