Peptide Database

Peptide NameTNS18

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC24H49N7O5

DescriptionStandard

        KKLK
    

Molecular Weight515.69 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.6893

GRAVY Index-1.98

Hydrophobic Moment 0.76

Boman Index-0.86

Instability Index-34.95

Aliphatic Index 97.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 228.68

LogP -0.71

H-bond Donors 8.0

H-bond Acceptors 8.0

Rotatable Bonds 21.0

Heavy Atoms 36.0

Ring Count 0.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0296539 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configbranched peptide architecture [Branched]

Chiralitycanonical L-amino-acid peptide [L]

Other Modsside-chain decanoylated lysine.; branching lysine, O = ornithine, B = diaminobutyric acid, K(C10) = side-chain decanoylated lysine.

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetPseudomonas aeruginosa PEJ2.6

Activity4 μg/mL

MethodMIC

RECORD: Rec_0330676 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configbranched peptide architecture [Branched]

Chiralitycanonical L-amino-acid peptide [L]

Other Modsside-chain decanoylated lysine.; branching lysine, O = ornithine, B = diaminobutyric acid, K(C10) = side-chain decanoylated lysine.

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetAcinetobacter baumannii ATCC 19606

Activity8 μg/mL

MethodMIC

RECORD: Rec_0406325 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configbranched peptide architecture [Branched]

Chiralitycanonical L-amino-acid peptide [L]

Other Modsside-chain decanoylated lysine.; branching lysine, O = ornithine, B = diaminobutyric acid, K(C10) = side-chain decanoylated lysine.

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetEscherichia coli W3110

Activity8 μg/mL

MethodMIC

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