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MYP_098609
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Basic Information
TNS18
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
4 amino acids
C24H49N7O5
Standard
Sequence
KKLK
Physicochemical Analysis
515.69 Da
10.30
2.76
2.55
0.6893
-1.98
0.76
-0.86
-34.95
97.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
228.68
-0.71
8.0
8.0
21.0
36.0
0.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017743 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
branched peptide architecture [Branched]
canonical L-amino-acid peptide [L]
side-chain decanoylated lysine.; branching lysine, O = ornithine, B = diaminobutyric acid, K(C10) = side-chain decanoylated lysine.
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa PEJ9.1
16 μg/mL
MIC
PMID29767453 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29767453/
RECORD: Rec_0052953 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
branched peptide architecture [Branched]
canonical L-amino-acid peptide [L]
side-chain decanoylated lysine.; branching lysine, O = ornithine, B = diaminobutyric acid, K(C10) = side-chain decanoylated lysine.
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas aeruginosa ZEM-9A
8 μg/mL
MIC
PMID29767453 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29767453/
RECORD: Rec_0062390 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
branched peptide architecture [Branched]
canonical L-amino-acid peptide [L]
side-chain decanoylated lysine.; branching lysine, O = ornithine, B = diaminobutyric acid, K(C10) = side-chain decanoylated lysine.
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
C. freundii bla OXA-48
8 μg/mL
MIC
PMID29767453 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29767453/
RECORD: Rec_0079146 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
branched peptide architecture [Branched]
canonical L-amino-acid peptide [L]
side-chain decanoylated lysine.; branching lysine, O = ornithine, B = diaminobutyric acid, K(C10) = side-chain decanoylated lysine.
Bio-Activity Profile
Hemolytic
human RBCs
500 μg/mL
MHC
PMID29767453 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29767453/
RECORD: Rec_0081061 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
branched peptide architecture [Branched]
canonical L-amino-acid peptide [L]
side-chain decanoylated lysine.; branching lysine, O = ornithine, B = diaminobutyric acid, K(C10) = side-chain decanoylated lysine.
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
E. cloacae bla NDM
16 μg/mL
MIC
PMID29767453 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29767453/
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