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MYP_098552
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Basic Information
P18K
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C90H171N27O22
Standard
Sequence
GILKTIKSIASKLKRKAK
Physicochemical Analysis
1983.49 Da
11.43
6.75
6.54
0.3752
-0.33
0.70
-0.22
14.67
119.44
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
836.73
-7.06
31.0
29.0
76.0
139.0
0.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0013597 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
50 μg/mL
MIC
PMID26901176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26901176/
RECORD: Rec_0168663 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
50 μg/mL
MIC
PMID26901176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26901176/
RECORD: Rec_0237919 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae ST258
50 μg/mL
MIC
PMID26901176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26901176/
RECORD: Rec_0290585 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
50 μg/mL
MIC
PMID26901176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26901176/
RECORD: Rec_0295371 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Human erythrocytes
80 μM
EC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/23403131/ PMID23403131 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23403131/
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