Peptide Database

Peptide Namep9

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Anti-Pneumovirus ▸ Anti-RSV

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC66H120N24O15S3

DescriptionStandard

        HRILMRIRQMMT
    

Molecular Weight1586.01 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)2.85

Net Charge (pH 7.4) 2.59

Charge Density (pH 7.0) 0.2373

GRAVY Index-0.20

Hydrophobic Moment 0.65

Boman Index-0.26

Instability Index30.18

Aliphatic Index 97.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 661.12

LogP -4.47

H-bond Donors 25.0

H-bond Acceptors 22.0

Rotatable Bonds 56.0

Heavy Atoms 108.0

Ring Count 1.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409492 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic peptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralityall-D amino-acid peptide [D]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Anti-RSV Replication inhibition

TargetPorcine reproductive and respiratory syndrome virus (PRRSV) | MARC-145 cells

Activity16.12 μM

MethodIC50

PaperAntiviral activity of phage display selected peptides against Porcine reproductive and respiratory syndrome virus in vitro. | Liu K, Feng X, Ma Z, Luo C, Zhou B, Cao R, Huang L, Miao D, Pang R, He D, Lian X, Chen P. | Virology. 2012 Oct 10;432(1):73-80. | DOI:10.1016/j.virol.2012.05.010 | PMID:22743126 PMID22743126 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22743126/

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