Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC384H596N100O104S8

DescriptionStandard

        MRVLFLIFGVLYLLSTVPPARSFIYIDECPSEYYNCRMKCNADEHAIRYCDDWTICCKLKYIEIEKQKRGR
    

Molecular Weight8533.97 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)1.54

Net Charge (pH 7.4) 1.15

Charge Density (pH 7.0) 0.0216

GRAVY Index-0.15

Hydrophobic Moment 0.56

Boman Index-0.03

Instability Index55.48

Aliphatic Index 87.89

Aromaticity 0.1408

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3307.42

LogP -21.86

H-bond Donors 123.0

H-bond Acceptors 115.0

Rotatable Bonds 280.0

Heavy Atoms 596.0

Ring Count 15.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240734 VERIFIED: NO

Provenance & Taxonomy

OrganismPiliocolobus tephrosceles [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence