Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC373H606N114O109S8

DescriptionStandard

        MKKAFKRSKIEETSKCHQGYGVCRDRCRKDETEVHFCRNNRRCCIKSDSTILTNVIAKEIEWPRLITTSMPFY
    

Molecular Weight8688.02 Da

Isoelectric Point (pI)9.35

Net Charge (pH 7.0)6.63

Net Charge (pH 7.4) 6.19

Charge Density (pH 7.0) 0.0908

GRAVY Index-0.78

Hydrophobic Moment 0.53

Boman Index-0.28

Instability Index60.22

Aliphatic Index 57.40

Aromaticity 0.0822

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3688.50

LogP -38.79

H-bond Donors 139.0

H-bond Acceptors 126.0

Rotatable Bonds 298.0

Heavy Atoms 604.0

Ring Count 11.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0185151 VERIFIED: YES

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal