Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC416H675N115O127S10

DescriptionStandard

        MKAINTALFLLAIVLVASSTSGVMAATKLRNAKYFQDTCLEVIYPGAPSCDEGECNTRCRSKYKGGVGHCIRTDCKCIYTCTIPSPAPSN
    

Molecular Weight9640.15 Da

Isoelectric Point (pI)8.67

Net Charge (pH 7.0)3.51

Net Charge (pH 7.4) 3.10

Charge Density (pH 7.0) 0.0390

GRAVY Index0.07

Hydrophobic Moment 0.50

Boman Index0.07

Instability Index50.43

Aliphatic Index 78.11

Aromaticity 0.0667

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3865.29

LogP -44.33

H-bond Donors 143.0

H-bond Acceptors 142.0

Rotatable Bonds 312.0

Heavy Atoms 668.0

Ring Count 12.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0025549 VERIFIED: NO

Provenance & Taxonomy

OrganismLeersia perrieri [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence